Interesting idea.
I played through crippled, was fine.
played most of illiterate, as long as you dont care about the signs you can do it well enough, accidentally hit reset before the end didn't get the badge.
THEN we come to spaztic.
I see what you were going for there. BUT you needed to space the timing out a BIT farther apart between 'siezures'. I was going good, the occasional death. Then I hit the room with the wall of fireballs. 20 deaths... THEN the game had me go back 5 rooms, THEN I had to sit there holding right 5 five minutes because of non stop spaz left/jump left attacks... Then it started overriding my 'go right' key which had been making me stand still, costing me another 2 rooms. I said 'well screw this'.
I see what you were going for. Daring in thought but horribly, HORRIBLY implimented.
As for some of the crippled dialoge it just got... repedative and annoying to scroll through. Example 'rot' guy. I see them saying it 2 or 3 times but having to mash the button 20, 30 times? no thanks.